Dr. Sabina Wachira

Dr Sabina

Designation: Registrar 

Dept.: Research, Technology Management and Community Linkages

Contact: Dedan Kimathi University Of Technology, P.O Box 657-10100, Nyeri, Kenya

Email: sabina.wachira@dkut.ac.ke; swachira2013@gmail.com

Academic Background

Qualification Institution Year
Master of Arts in Project Planning and Management (MAPPM) University of Nairobi, Kenya 2013
Post-doctoral training (Natural Product Chemistry) University of Cambridge/ Kenya Medical Research Institute/ International Centre for Insect Physiology and Ecology (icipe) 2011- 2013
PhD in Chemistry Jomo Kenyatta University of Agriculture and Technology, Kenya 2010
Master of Science in Chemistry University of Dar es Salaam, Tanzania 2001
Bachelor of Science Degree (B.Sc. Hons), Second Class Honours Upper Division, Chemistry major and Mathematic minor University of Nairobi, Kenya 1998

 

Research Interests
•Cancer research, use of natural  product for drug development in a sustainable way for both communicable and non communicable diseases
•Monitoring and evaluation for research based project

Professional Qualifications

Qualification Institution Year
Monitoring and Evaluation (M&E) Certification Kenya Institute of Management, Kenya 2015

Areas of Expertise:
Project management, Monitoring and Evaluation, organic chemistry 

Work Experience

Dedan Kimathi University of Technology Nov 2014-To Date: Registrar Research, Technology Management and Community Linkages (RTMCL)

Centre for Traditional Medicine and Drug Research (CTMDR),

Kenya Medical Research Institute(KEMRI)

Aug. 2002 to Oct 2014 Senior Research Officer and Chemical Science Unit Head

Other University and National Responsibilities
i.Member of organizing committee of the 2nd DeKUT International Conference on Science, Technology, Innovation and Entrepreneurship October 2015-November 2016
ii.Chairing knowledge management committee of Dedan Kimathi University of Technology November 2014-June 2017

Publications
i)Peer Reviewed Journal Publications

a. Wachira Sabina Wangui, Kidombo Harriet, Kinyua Jesse Maina (2015) Factors Influencing Successful Implementation of Biomedical Research Projects: A Case of Kenya Medical Research Institute. Researchjournali’s Journal of Public Policy. Vol. 2, No. 2 August, 2015. http://www.researchjournali.com/pdf/1957.pdf
b. Rotich C. K., Nyangacha R. M., Wachira S.W., Ngeiywa M. M. and Kigondu E. V.M. (2015). Antimalarial activities and toxicity levels of selected medicinal plants used in Kenya. African Journal of Pharmacology and Therapeutics 4 (3): 92-100. http://journals.uonbi.ac.ke/ajpt/article/view/1361
c. Nabende P.N., Karanja S.M., Mwatha J.K. and Wachira S.W. (2015). Anti-proliferative Activity of Prunus africana,Warburgia stuhlmannii and Maytenus senegalensis Extracts in Breast and Colon Cancer Cell Lines. European Journal of Medicinal Plants. 5(4): 366-376,Article no.EJMP.2015.035. http://www.sciencedomaine.org/abstract/7250
d. Karori M., Wachira F., Ngure R., Mireji P., Wachira S. (2014). Antimutagenic effect of Kenyan Tea cultivars in a bacterial test system. The Pharma Innovation Journal 3(8): 94-100. http://www.thepharmajournal.com/vol3Issue8/Issue_oct_2014/13.1.pdf
e. Wachira S.W., Omar A.S., Wanjiru J.J., Wahome M., Alborn T.H., Spring R.D., Masiga D.K., Torto B. (2014). Toxicity of six plant extracts and two pyridone alkaloids from Ricinus communis against the malaria vector Anopheles gambiae. Parasites & Vectors 2014, 7:312 (4 July 2014). doi: 10.1186/1756-3305-7-312
f. Wachira S.W., Ndung’u M., Njagi P., Hassanali A. (2010). Comparative responses of ovipositing Anopheles gambiae and Culex quinquefasciatus females to the presence of Culex egg rafts and larvae. Medical and Veterinary Entomology, Volume 24, Issue 4, pages 369–374. doi: 10.1111/j.1365-2915.2010.00913.x.
g. Odebode A.C., Jonker S.A., Joseph C.C., Wachira S.W. (2006). Anti-fungal activities of constituents from Uvaria scheffleri and Artabotrys brachypetalus. Journal of Agricultural sciences, volume 51, No 1, pages 79-86. http://www.doiserbia.nb.rs/img/doi/1450-8109/2006/1450-81090601079O.pdf
h. Mayunga H.H. NKunya, Stephan A. Jonker , Rene de Gelder, Sabina W. Wachira, Charles Kihampa (2004). (+/-)-Schefflone: a trimeric monoterpenoid from the root bark of Uvaria scheffleri. Phytochemistry. 65(4):399-404. http://www.sciencedirect.com/science/article/pii/S0031942203006356

ii)Publications in conference proceedings

i.Wachira S.W., Ndung’u M., Njagi P., Hassanali A. (2011). Comparative responses of ovipositing Anopheles gambiae  and Culex quinquefasciatus females to the presence of Culex egg rafts and larvae a paper presented on SEMIO-11 symposium in icipe TRO hall on 12th -15th  November at Nairobi, Kenya. Semio-11 Workshop book of abstract p. 81
ii.Wachira S.W., Ndung’u M., Njagi P., Hassanali A. (2009). Chemical signals influencing oviposition of the malaria mosquito, Anopheles gambiae. 30th African Health Sciences Congress. Accra Ghana book of abstract p. 3 (SSI-V). Conference date 14th -16th October
iii.Wachira S.W., Ndung’u M., Hassanali A., Njagi P. (2009). Interspecific chemical signals influencing oviposition of malaria mosquito, anopheles gambiae. Jomo Kenyatta University of Agriculture and Technology scientific conference proceedings p. 14. Conference date 5th-6th May

 Papers presented in conferences, seminars and workshops

i.Wachira S.W.(2015). Decolonization of our health system: The role of Traditional Medicine in the Fight Against Cancer-A Research perspective. Paper presented on 2nd DeKUT International Conference On African Liberation Efforts, 18th -20th February, Dedan Kimathi University of Technology, Nyeri, Kenya
ii.Wachira S.W. & Matu E. N. (2013). African Traditional Medicine in the Fight Against HIV/AIDS in Kenya : A Research perspective. Oral presentation in HelpAge Regional Consultative Meeting on Traditional Health Practitioners (THPs) and Traditional Leaders/Community Leaders (TLs/CLs) 19th – 21st November  Nairobi, Kenya
iii.Wachira S.W., Spring D., Omar A.S., Masiga D., Torto B. (2012). Exploiting mosquito phytoceuticals for malaria control. A Paper presented at the University of Cambridge Springs group 10th May.

Awards, Scholarships  and Recognitions

 •PhD Scholarship: Dutch Government (Netherlands-SII) through ICIPE under African Regional postgraduate Programme in Insect Science  (ARPPIS)- Sep 2005-Feb 2009
•Masters Scholarship: Competitive holder of DAAD NAPRECA scholarship-1999-2001
•First prize award for the best poster presentation in the 9th Natural Products Research Network for Eastern and Central Africa (NAPRECA) Symposium held on Aug. 26-31 2001 in Nairobi, Kenya organized by DAAD NAPRECA

Other Academic and Professional Achievements

• Chairing a session in 2nd  DeKUT International Conference on African Liberation Efforts  18– 20 February, 2015
• Manuscript reviewer international Journal- Parasites and vectors 2014
• Member of National organizing committee of the 1st International Conference on Pesticidal Plants May 2011-January 2013
• Appointed as a temporary adviser in the 5th MIM  Pan Africa Malaria Conference held in Nairobi, Kenya, November 2-6, 2009

Research

a)Ongoing/Completed Researches
Exploiting anti-cancer potential of three medicinal plants traditionally used in Kenya. This includes: In-vitro testing of the extracts from three Kenyan medicinal plants against breast and prostate cancer cell line. Determining the anticancer activity of blends prepared by combining the extracts. Screening the active extract and blends of the three plants for acute and chronic in vivo toxicity and developing GC-MS, HPLC and TLC fingerprints for quality assurance.

b) Research funding
i.THRiVE 2nd equipment grant for Microplate reader amounting to £7,800, Principal Investigator (PI), Wellcome Trust through Training Health Researchers into Vocational Excellence (THRiVE) consortium, August 2012
ii.Grant in support of research entitled “Exploiting anti-cancer potential of three medicinal plants traditionally used in Kenya” amounting to 33000 USD, PI, National Commission for Science, Technology and Innovation (NACOSTI), April 2012
iii.THRiVE 1st equipment grant for an insect growth chamber amounting to £14,000, PI, Wellcome Trust Through THRiVE consortium, July 2011
Two year postdoctoral research fellowship, grant number 087540 amount £71,255. Title of the project “Exploiting mosquito phytoceuticals for malaria control”, PI, Wellcome Trust Through THRiVE consortium, Principal Investigator, Feb. 2011-Jan. 2013

Postgraduate Thesis Supervision

i) Doctorate
• Misonge Jared Onyancha, Kenyatta University, Department of Pharmacy/Alternative Complementary Medicine, PhD ongoing 2014: Evaluation of anticancer activity of some medicinal plants used for management of cancer by traditional medical practitioners in Kenya
ii) Masters
• Patricia Namukhosi Nabende, JKUAT, ITROMID, completed 2015: Safety and evaluation of anti-proliferative activity of Prunus africana, Warbugia stuhlmannii and Maytenus senegalensis in breast and prostate cancer cell lines
• Charles Kipchirchir Rotich, Eldoret University, Department of Biological Science, completed 2015: In vitro and in vivo antimalarial activities and toxicity studies of selected plants used in Kenya
• Gladys Wanjiru Maina, Kenyatta University, Department of Chemistry, Masters Ongoing 2015: Investigation of Anticancer Activity of Uvaria scheffleri, Artemisia afra and Azadirachta indica against Breast and Prostate Cancer Cells Line

Postgraduate Thesis Examination

• Wamakima Hannah Nyakio, KU 2015 M.Sc. thesis entitled “Synthesis and antimalarial evaluation of a quinoline-trioxane hybrid drug” Masters of Science Degree in Chemistry
• Wachira Benson Mureithi, KU 2015 M.Sc. thesis entitled “Repellence studies of delta-octalactone analogues and blends against Glossina pallidipes and Glossina morsitans morsitans” Masters of Science Degree in Chemistry
• Godfrey Nattoh, PAU/JKUAT 2014 M.Sc. thesis entitled “Bioprospecting suitability of selected basidiomycetes for biocoloration and bioremediation potential” Masters of Science Degree in Molecular and Biotechnology
• Ndirangu Githui Ephantus, KU 2014 M.Sc. thesis entitled “Repellence of Essential Oil of Nigella sativa Seeds against Anopheles gambiae and Identification of the Active blend” Masters of Science Degree in Chemistry

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